Facile and efficient one-pot synthesis of benzimidazoles using lanthanum chloride

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Facile and efficient one-pot synthesis of benzimidazoles using lanthanum chloride

BACKGROUND We report the synthesis of benzimidazoles using lanthanum chloride as an efficient catalyst. One-pot synthesis of 2-substituted benzimidazole derivatives from o-phenylenediamine and a variety of aldehydes were developed under mild reaction conditions. RESULTS We have examined the effect of different solvents using the same reaction conditions. The yield of the product varied with t...

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ژورنال

عنوان ژورنال: Organic and Medicinal Chemistry Letters

سال: 2013

ISSN: 2191-2858

DOI: 10.1186/2191-2858-3-7